Meet The Stars Who’ll Be Telling The Gross Truth About Puberty On Netflix’s ‘Big Mouth’

Netflix's Big Mouth is anchored by a host of major comedians — Nick Kroll, John Mulaney, Maya Rudolph, Jessi Klein — but the Big Mouth celebrity guest cast is just as stacked. Among those featured are Kristen Bell, Jon Hamm, Kristen Wiig, and Mark Duplass, so it's basically a who's who of Hollywood for viewers adept at picking out voices.

The series, an animated sitcom, was created by Kroll alongside Family Guy writer Andrew Goldberg and husband-wife duo Mark Levin and Jennifer Flackett, the latter of whom have worked together on films like Journey to the Center of Earth (2008) and Wimbledon (2004). It's based on real-life pals Kroll and Goldberg's teenage years, and, judging by the trailer, is the streaming equivalent of an Adult Swim show: An unfiltered, foul-mouthed dive into the dreadfully hormonal rite of passage called puberty.

It chronicles the exploits of Kroll's fictional self, Nick Birch, and his extended group of friends, family, and classmates. Fred Armisen (Portlandia) voices his father, Elliot; Maya Rudolph (Maya & Marty) both his mother, Diane, and Connie the Hormone Monstress (Kroll also plays her male counterpart, Maurice the Hormone Monster); John Mulaney (Saturday Night Live) his friend Andrew; Jenny Slate (Girls) Missy; Jason Montzoukas (The League) Jay; Jessi Klein (Inside Amy Schumer) Jessi; and Jordan Peele (Key and Peele) the ghost of Duke Ellington, among several other characters.

And somewhere along the way, these other famous voices will join them.

Kat Dennings

In her first role post-2 Broke Girls, Kat Dennings guests for four episodes as Leah.

Kristen Bell

Keep an ear out for Kristen Bell as two characters — listed only as "pillow" and "girl" — in three episodes.

Chelsea Peretti

Chelsea Peretti, who's notably married to star Jordan Peele, voices Monica in three episodes.

Kristen Wiig

Kristen Wiig pauses from her voice work on the How to Train Your Dragon franchise to play a talking vagina in Episode 5, "Girls Are Horny Too."

Zach Woods

Silicon Valley star Zach Woods voices Daniel in Episode 8, "Mid-Childhood Crisis."

June Diane Raphael

June Diane Raphael — who plays Brianna Hanson in fellow Netflix series Grace and Frankie — voices Devin in four episodes.

Nasim Pedrad

People of Earth and New Girl vet Nasim Pedrad stops in mid-season as Fatima, MS, and Raths in Episode 5, "Girls Are Horny Too."

Mark Duplass

Mark Duplass (Manhunt: Unabomber, The Mindy Project) voices Val and Clerk in two episodes.

Alia Shawkat

Arrested Development's Alia Shawkat voices Roland in Episode 6, "City Kids."

Paul Scheer

Paul Scheer (Veep, Fresh Off The Boat) lends his voice to two episodes.

Mae Whitman

Having contributed to animated series like Family Guy, DC Super Hero Girls, and Teenage Mutant Ninja Turtles, Parenthood alum Mae Whitman has an extensive voice acting resume. Here, she voices Tallulah in Episode 8, "Mid-Childhood Crisis."

Jon Hamm

Jon Hamm pops up in the penultimate episode, "I Survived Jessi's Bat Mitzvah," as a character named Scallops.

Craig Robinson

Ghosted star (and Office favorite) Craig Robinson voices a handful of characters in the finale.

Jack McBrayer

Listen for Jack McBrayer — who 30 Rock fans will remember as lovable doofus Kenneth Parcell — in the finale, too.

Beyond names, details about each of their characters remain sparse, but with the show's Sept. 29 premiere quickly approaching, it won't be long until you can marathon your way through the full 10 episodes. One thing you can count on? With this much star power behind it, Big Mouth should be just as hilarious, sharp, and wildly inappropriate as the trailer seems to suggest, so prepare yourself for a wonderfully weird addition to the Netflix lineup.